Clinical Monograph • Medically Reviewed
Ventolin HFA
Albuterol Sulfate Inhalation Aerosol • Short-Acting Beta-2 Adrenergic Agonist (SABA)
Clinical Overview: Rapid-acting selective beta-2 receptor agonist bronchodilator for prompt reversal of acute bronchospasm and bronchoconstriction.
Therapeutic Indications & Pharmacodynamics
Stimulates intracellular adenyl cyclase, catalyzing conversion of ATP to cyclic AMP (cAMP). Elevated cAMP levels relax bronchial smooth muscle, inhibit release of mast cell mediators, and restore pulmonary airway patency within 5 minutes.
Clinical Indications
Acute treatment and prevention of bronchospasm in patients with reversible obstructive airway disease (asthma, COPD), prevention of exercise-induced bronchospasm (EIB).
Contraindications & Precautions
Hypersensitivity to albuterol sulfate or fluorocarbon propellant formulations.
Prescribing Profile
Available Strengths:
90mcg per actuation (200 metered actuations)
90mcg per actuation (200 metered actuations)
Elimination Half-Life:
3.8 to 5 hours
3.8 to 5 hours
Reviewing Physician:
Dr. Caroline Hernandez, MD
Dr. Caroline Hernandez, MD